原发性肾小球疾病简称 PGD 中的发病机理十分复杂,与机体的免疫、凝血、纤溶和激肽系统都有密切关系,许多研究表明,凝血过程变化对原发性肾小球疾病的发生发展均有极为重要的影响。表现为血浆凝固因子和血小板增多,凝血酶和纤溶酶原降低,因此血液凝固性增多。PGD 患者血液粘滞度增高,常处于高粘聚状态,为了寻找高粘聚状态的客观指标我们对34例患者作了体外血栓形成观察。在心血管疾病中血栓形成报导较多,而对 PGD患者血栓形成研究尚较少见。血栓形成与血流动力学特性有密切关系。1958年 Chadle 首先发明了一种体外形成人工血栓装置,同体内形成血栓有类似 Primary glomerular disease PGD in the pathogenesis is very complicated, and the body’s immune, coagulation, fibrinolysis and kinin system are closely related to many studies have shown that coagulation changes in primary glomerular disease The development and development have a very important impact. The performance of plasma coagulation factor and thrombocytosis, thrombin and plasminogen decreased, so blood coagulation increased. PGD ​​patients with increased blood viscosity, often in a state of high cohesion, in order to find an objective indicator of high cohesion state of 34 patients were made in vitro thrombosis observation. Thrombosis in cardiovascular disease more reported, while the study of thrombosis in patients with PGD is still rare. Thrombosis and hemodynamic properties are closely related. In 1958 Chadle first invented an in vitro formation of artificial thrombosis device, similar to the formation of thrombus in vivo