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目的研究脑部转移肿瘤使用显微配合框架立体定向技术进行手术的效果分析。方法对18例脑转移肿瘤患者使用显微配合框架立体定向技术进行手术,术后进行常规方法的全脑放疗。结果 18例患者中,16例肿瘤全切,2例肿瘤大部分切除,手术过程无1例死亡。术后随访3个月,11例神经症状达到完全缓解,4例达到部分缓解,2例无变化,1例恶化,整体缓解率达到83.3%;局部复发率为22.2%;存活率为1年55.6%,2年为22.2%,3年为11.1%,半数生存期为13.5个月。结论显微配合框架立体定向微创技术进行手术治疗脑部转移肿瘤的治疗效果令人满意,可以减轻患者疾病痛苦。
Objective To study the effect of microsurgical frame stereotactic technique for surgical treatment of brain metastases. Methods Eighteen patients with brain metastases were treated with microsurgical frame stereotactic technique and received conventional method of whole brain radiotherapy. Results Among the 18 patients, 16 cases were completely resected and 2 cases were resected. None of them died during the operation. After 3 months of follow-up, neurological symptoms of 11 patients achieved complete remission, partial remission in 4 patients, no change in 2 patients and deterioration in 1 patient. The overall response rate was 83.3%. The local recurrence rate was 22.2%. The survival rate was 55.6 %, 22.2% in 2 years, 11.1% in 3 years, and 13.5 months in half of the patients. Conclusion Microsurgical treatment with stereotactic minimally invasive stent implantation for the treatment of brain metastases is satisfactory and can alleviate the suffering of patients.