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目的掌握2004年湖北地区流感流行状况。方法收集及分析监测医院及暴发疫情资料,用鸡胚和细胞培养分离并鉴定流感病毒,用血球凝集抑制试验检测人群中抗流感病毒抗体水平。结果监测医院2004年流感样病例较往年增加,冬春和夏季可见2个波峰;各地报告发生疫情35起,15起疫情有56人经实验室检测确诊为流感病例,80%发生在中小学校;全年从936份标本中分离病毒123株,甲3型95株(占77.2%),乙型(yamagata株系)流感病毒28株(占22.8%);正常人群抗体水平测定以抗甲3抗体最高,抗甲1抗体最低。结论2004年湖北省流感活动较为活跃,流行毒株以甲3型病毒为主,并有向乙型转化的趋势。
Objective To master the epidemic situation of influenza in Hubei in 2004. Methods The surveillance hospital and outbreak data were collected and analyzed. Influenza virus was isolated and identified by chicken embryo and cell culture. The anti-influenza virus antibody level in the population was detected by hemagglutination inhibition test. Results The number of influenza-like cases in the surveillance hospitals increased from 2004 to 2004 with two peaks in winter, spring and summer. Of the 35 reported cases of outbreaks in the area, 56 were confirmed as influenza cases by laboratory tests and 80% in primary and secondary schools. A total of 123 strains of viruses were isolated from 936 specimens, including 95 strains (77.2%) of type A and 28 (22.8%) strains of influenza B (type 2) (yamagata strain). Antibody against normal T3 Highest, lowest anti-A 1 antibody. Conclusion The influenza activity in Hubei province was relatively active in 2004, and the predominant strain of virus was type A 3, with a trend of converting to type B.