张××，女，44岁。因风湿性关节炎（活动期）予青霉素静点7天末效，改用头抱哩批钠静脉点滴6天仍未见明显好转。换用骨宁2ml肌肉注射1日2次，第一针下午7点注射，到夜间12点左右开始肚脐及两乳头发痒，发现有少许散在米粒大小的红疹。第二天上午11点又注射第二针，注射后约3小 Zhang X, female, 44 years old. Due to rheumatoid arthritis (active period) to penicillin 7 days after the end of the static effect, change to use the head and hold the phlegm sodium intravenous drip 6 days still no significant improvement. Intramuscular injection of 2 ml of Bone Ning 2 times a day, the first shot 7:00 pm, to start the navel and breast milk itching around 12 o’clock at night, found a little scattered in the size of rice rash. The second shot was injected at 11am the next morning, about 3 small hours after the injection