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目的:探讨剖宫产后早孕药物流产加服米非司酮是否能提高完全流产率。方法:剖宫产后再次妊娠(停经≤49 d)行药物流产的孕妇240例,随机分为研究组和对照组。对照组120例,米非司酮75 mg/d(早50 mg,晚25 mg)连用2 d,第3日口服米索前列醇600μg;研究组120例,在对照组的基础上,服用米索前列醇后加服米非司酮25 mg,bid×3 d。结果:研究组和对照组的完全流产率分别为92.50%和73.33%,差异有统计学意义(P<0.01),阴道流血时间分别为11.0±4.0 d和14.7±5.4 d,差异有统计学意义(P<0.01)。结论:剖宫产后早孕药物流产加服米非司酮25 mg,bid×3 d,可提高完全流产率,缩短阴道流血时间。
Objective: To investigate if abortion after early cesarean section with abortion mifepristone can increase the rate of complete abortion. Methods: 240 pregnant women undergoing cesarean section after pregnancy (menopause ≤ 49 d) were randomly divided into study group and control group. Control group of 120 cases, mifepristone 75 mg / d (as early as 50 mg, night 25 mg) for 2 d, the third day of oral misoprostol 600μg; study group 120 cases, on the basis of the control group, taking rice Supramoetine plus mifepristone 25 mg, bid × 3 d. Results: The complete abortion rates of the study group and the control group were 92.50% and 73.33%, respectively, with statistical significance (P <0.01). The vaginal bleeding time was 11.0 ± 4.0 days and 14.7 ± 5.4 days respectively, with significant difference (P <0.01). Conclusion: After abortion, abortion may increase the rate of complete abortion and shorten the time of vaginal bleeding after medical abortion plus mifepristone 25 mg, bid × 3 d.