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背景 卫生经费投入的下降要求卫生机构探索或选择更加经济的药物治疗方案。格列本脲与格列吡嗪的疗效相同,但其日费用约为后者的一半。纽约Bronx市立医院制定和实施了格列本脲替代格列吡嗪的改革方案。 目的 了解该方案实施前后血糖控制的效果、高危老年用药者的安全性和药费的变化。 对象 在Bronx医院3个门诊药房取药的、享受医疗补助计划资助的坚持服用格列吡嗪的病人;高危病人——年龄≥65岁并有肝或肾功能损害者,或需用胰岛素治疗者除外。入选病例78人,男女各半,33例年龄≥65岁。
The decline in background health funding requires health agencies to explore or choose more cost-effective drug treatment options. Glibenclamide and glipizide the same effect, but the daily cost is about half of the latter. Bronx Municipal Hospital in New York developed and implemented a replacement program for glibenclamide instead of glipizide. Objective To understand the effects of glycemic control before and after the implementation of the regimen and the safety and drug costs of high-risk elderly drug users. Subjects who were admitted to the three outpatient pharmacies at Bronx Hospital who were insisted on graphenazine supported by the Medicaid program; those at high risk of age who were 65 years of age or who had impaired liver or kidney function, or those who required insulin therapy except. 78 selected patients, half male and half female, 33 patients ≥65 years of age.