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目的探讨胃肠道恶性淋巴瘤的诊治方法。方法对24例胃肠道淋巴瘤资料进行了回顾性分析。结果小肠淋巴瘤13例,3例术前在CT引导下活检确诊,11例钡餐检查8例异常;胃淋巴瘤6例与结肠淋巴瘤5例均为术前内窥镜下活检确诊。B超检查22例,14例阳性;CT检查17例,14例阳性。23例行手术治疗辅佐CHOPE化疗,有效率958%。术后全部病例均获随访,随访时间为1~14年,5年生存率为667%。Ⅱ,Ⅲ期9例术后6~23月复发,5例死于复发与并发症。结论内窥镜下活检或CT引导下活检最具确诊价值,消化道钡餐对诊断有所帮助。治疗以手术作为首选,辅佐化疗,以CHOPE方案为佳。
Objective To investigate the diagnosis and treatment of gastrointestinal lymphoma. Methods 24 cases of gastrointestinal lymphoma were retrospectively analyzed. Results Intestinal lymphoma was found in 13 cases, 3 cases were confirmed by CT-guided biopsy before operation, 11 cases of barium meal examination were abnormal, and 6 cases of gastric lymphoma and 5 cases of colon lymphoma were confirmed by preoperative endoscopic biopsy. B-ultrasound examination in 22 cases, 14 cases were positive; CT examination in 17 cases, 14 cases were positive. Twenty-three patients were treated with CHOPE chemotherapy with an effective rate of 95.8%. All patients were followed up for a period of 1 to 14 years. The 5-year survival rate was 66.7%. II, III 9 cases of recurrence after 6 to 23 months, 5 cases died of recurrence and complications. Conclusion The endoscopic biopsy or CT-guided biopsy is the most definitive diagnosis, and barium meal in the digestive tract is helpful for diagnosis. Treatment as the first choice for surgery, adjuvant chemotherapy, better with CHOPE program.