通常发病缓慢的脂溢性角化症,老年性血管瘤和多毛症等,突然发作增多(多数在6个月内)的病例中,并发内脏恶性肿瘤的发生率很高.作为突发性伴发恶性肿瘤的皮肤综合征有Lese-Trélat综合征(突发性角化病);多发性网状组织细胞增生症;后天性毳毛多毛症;Crow-Fukase综合征(突发性血管瘤);Bazex综合征(突发性肢端角化症).作者强调指出突发性皮肤病变的动态变化是重要的,不要认为是静止的 The incidence of concurrent visceral malignancies is often high in sudden cases of seborrheic keratosis, senile hemangiomas, and hirsutism, and sudden episodes increase (mostly within 6 months). Malignant neoplasms with Lese-Trélat syndrome (provokeratosis); multiple reticular histiocytosis; acquired hirsutism; Crow-Fukase syndrome (sudden hemangioma) ; Bazex syndrome (emergency keratosis). The authors emphasize that dynamic changes in sudden cutaneous lesions are important and should not be considered static.