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目的 观察在急重症脑血管病中使用H2 受体拮抗剂西米替丁对应激性溃疡发生的预防作用。方法 :将12 2例急重症脑血管病人随机分为常规治疗的对照组和入院时即加西米替丁治疗而其它治疗原则相同的治疗组。比较急性期应激性溃疡出血的发生率 ,治疗组的发生率明显低于对照组 (P <0 .0 1)。结论 西米替丁能有效预防急重症脑血管病中应激性溃疡出血的发生
Objective To observe the preventive effect of cimetidine, an H2 receptor antagonist, on the development of stress ulcer in patients with acute cerebrovascular disease. Methods: One hundred and twenty-two patients with acute cerebrovascular disease were randomly divided into routine treatment control group and gatifloradine treatment while other treatment principles were the same. Comparing the incidence of acute stress ulcer bleeding, the incidence of treatment group was significantly lower than the control group (P <0. Conclusion Cimetidine can effectively prevent the occurrence of stress ulcer hemorrhage in acute cerebrovascular disease