Babaodan Capsule(八宝丹胶囊)Combined with Qingyi Huaji Formula(清胰化积方)in Advanced Pancreatic Cancer—A Feas

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Objective:To observe the clinical effects of Babaodan Capsule(八宝丹, BBD) combined with Qingyi Huaji Formula(清胰化积方,QYHJ) in treating patients with advanced pancreatic cancer.Methods:Eighty-one patients with advanced pancreatic cancer (from January 1,2013 to December 31,2014) were enrolled.Patients were assigned to two groups:QYHJ plus BBD group (40 cases) and QYHJ only group (41 cases),and there were no significant differences for other treatment between two groups.The survival and cancer-related symptoms were compared between two groups over two cycles of treatment.Results:The cancer-related symptoms of patients such as ascites,jaundice,pain,abdominal distension,anorexia and Kamofsky performance status of QYHJ plus BBD group were significantly improved as compared with those of the QYHJ group (P<0.01).In addition,the 1-year survival rate of patients in QYHJ plus BBD group was longer than that in the QYHJ group (65% vs.33%,respectively,P=0.0023).Conclusions:BBD with QYHJ is feasible treatment to prolong the survival of patients with advanced pancreatic cancer.However,it deserves to be further investigated in randomized clinical trials.
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The Fujian Academy of Integrative Medicine,located in the West Coast of the Taiwan Strait,was founded on July 3,2005 under the Chairmanship of Dr.CHEN Ke-ji,who is an academician of Chinese Academy of Sciences (CAS,Figure 1).With the mission of using new
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