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目的探讨肺曲霉病的临床表现和影像学特征,以提高对本病的认识.方法采用回顾性分析的方法对我院2006年1月至2012年8月37例诊断为肺曲霉病患者的临床资料进行分析研究.结果28例(75.68%)的肺曲霉病伴有基础疾病.临床主要表现为咯血、咳嗽、咳痰、气促、胸痛、发热.胸部 CT主要表现为高密度结节影、厚壁/不规则空洞、斑片阴影、钙化.病变部位主要集中在右肺上叶及左上肺.20例为确诊病例,胸腔镜或开胸肺切除术后病理确诊16例,电子支气管镜肺活检确诊7例.同时由电子支气管镜肺活检及肺切除术后病理报告3例.28例(75.67%)经手术及抗真菌治疗好转或痊愈.结论肺曲霉病多继发于全身基础疾病,临床表现特异性低,影像学表现多样,极易误诊,临床诊断应结合病史、临床表现、影像学及病理学检查,纤维支气管镜检查在该疾病的诊断中具有重要作用.“,”Objective To explore the clinical manifestations of pulmonary aspergilosis and imaging characteristics, in order to improve the understanding. Methods 37 patients with pulmonary aspergilosis admitted to our hospital from January 2006 to August 2012 were analyzed retrospectively on the clinical data .Results 28 cases (75.68%) with pulmonary aspergilosis had basic diseases. Most of these patients experienced haemoptysis, cough, sputum, shortness of breath, chest pain and fever . Chest CT main performanced high density nodules shadow, thick wal/irregular hole, patch shadow and calcification. The lesion mainly concentrated in the upper lobe and upper left lung. There were 20 confirmed cases, 16 cases were confirmed by thoracoscopy or open chest pneumonectomy pathology, 7 cases were diagnosed by electronic bronchoscope lung biopsy. 3 cases were diagnosed by electronic bronchoscope lung biopsy and pneumonectomy pathological . 28 cases (75.67%) became better or recovered after surgering and antifungal therapy.Conclusion Pulmonary aspergilosis many secondary entire body basic diseases, clinical manifestations and imaging lack of specific, easy misdiagnosis. clinical diagnosis should be combined with the history, clinical presentation, imaging and pathological examination, fiber bronchoscope examination in the diagnosis of the disease has an important role.