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本研究旨在评价唾液和血液HIV抗体检测的符合情况,并根据敏感性、特异性、安全性、简便及经济等比较唾液诊断在HIV诊断上的实用价值。在963份唾液标本中,检出阳性4例。使用Abbott试剂,其相对血液的敏感性和特异性均为100%,血清COV高于唾液COV,其平均值分别为0.084和0.042,但二者有明显的平行倾向。唾液检测简便、安全、经济、稳定且无害是开展大规模调查及哨点监测较为理想的检测方法。
The purpose of this study was to evaluate the compliance of HIV antibody tests in saliva and blood and to evaluate the diagnostic value of saliva in terms of sensitivity, specificity, safety, convenience and economy. In 963 saliva samples, 4 were positive. Using Abbott reagent, the relative blood sensitivity and specificity were 100%, serum COV higher than salivary COV, the average were 0.084 and 0.042, but the two had a clear parallel tendency. Saliva detection is simple, safe, economical, stable and harmless to carry out large-scale surveys and sentinel surveillance is an ideal test method.