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概述自 Zaccaelli 于1549年首次为一名脾肿大女病人成功地实行了脾切除术以来,脾切除术已在临床应用400余年了。但是,随着对脾脏免疫功能的深入研究以及对脾切后所带来弊端的观察(见附表),使人们对牌切除术的手术指证不得不提出挑战,尤其脾外伤的处理原则,已发生了深刻的变革。这是因为发生于70年代的大量实验研究及临床观察均足以说明:脾脏并非“留之无用,去之有益”的器官,它在抗感染免疫方面起着不可低估的作用。人类在漫长的进化中,这一非对称性器官却没有退化,这也许是脾脏的“天生我才必有用”的最好证明。
Overview Splenectomy has been in clinical use for more than 400 years since Zaccaelli successfully splenectomized for the first time in 1549 for a woman with splenomegaly. However, with the in-depth study of the immune function of the spleen and the observation of the drawbacks caused by splenectomy (see the attached table), it is imperative to challenge the surgical indications of brand resection, especially the treatment of splenic trauma A profound change took place. This is because a large number of experimental studies and clinical observations that took place in the 1970s are sufficient to show that the spleen is not a “useless, beneficial” organ that plays an important role in anti-infective immunity. In the long evolution of mankind, this non-symmetrical organ has not been degraded, which may be the best evidence that the spleen is “born of me”.