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本文采用随机双盲对照试验研究，试验组与对照组各１００例。试验组于产后４８ ｈ用缩宫素鼻喷雾剂对产妇一侧鼻孔喷入２喷。每隔２ ｈ喷一次，共３次。对照组用安慰剂代替缩宫素鼻喷雾剂，方法同前。分别于每次用药后５ ｍｉｎ和停药后２４ｈ观察总乳汁量、吸空时间、乳腺管通畅度及乳房结节等。以综合疗效评分为疗效判断标准。结果：试验组显效率４１％，有效率３７％，总有效率７８％，无效率２２％；对照组显效率６％，有效率２３％，总有效率２９％，无效率７１％。经统计学处理两组疗效有显著差异（Ｐ＜０．０１）。该药有明显促进乳腺管通畅作用，提高乳汁排出量和完全母乳喂养率，且未见药物不良反应，安全可靠。
In this paper, a randomized double-blind controlled trial study, the experimental group and the control group of 100 cases. The experimental group 48 h postpartum with oxytocin nasal spray on the maternal side of the nose spray 2 spray. Spray every 2 h, a total of 3 times. The control group with placebo instead of oxytocin nasal spray, the same way. The total milk volume, suction time, the degree of breast duct patency and breast nodules were observed 5 min after each treatment and 24h after stopping. A comprehensive evaluation of efficacy as a criterion for efficacy. Results: In the experimental group, the effective rate was 41%, the effective rate was 37%, the total effective rate was 78% and the ineffective rate was 22%. In the control group, the effective rate was 6%, the effective rate was 23%, the total effective rate was 29%, and the ineffective rate was 71%. The statistical difference between the two groups was significant (P <0.01). The drug has a clear role in promoting patency of the mammary duct, increase milk output and complete breastfeeding rate, and no adverse drug reactions, safe and reliable.