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Cutaneous involvement with Hodgkin’ s disease in HIV-po-sitive patients is infrequent. Although the large majority of these cases are pathogenetically linked to Epstein-Barr virus, demonstration of viral oncogenes in skin involvement of Hodgkin’ s disease has rarely been performed. We reportated an HIV-positive male with aggressive Hodgkin’ s disease and specific cutaneous involvement. The presence of Epstein-Barr virus in cutaneous and lymph node samples could be demonstrated by a positive reaction to the Epstein-Barr virus latent-encoded membrane protein.
Cutaneous involvement with Hodgkin’s disease in HIV-po-sitive patients is infrequent. Although the large majority of these cases are pathogenetically linked to Epstein-Barr virus, demonstration of viral oncogenes in skin involvement of Hodgkin’s disease has been performed. We reportated an HIV-positive male with aggressive Hodgkin’s disease and specific cutaneous involvement. The presence of Epstein-Barr virus in cutaneous and lymph node samples could be demonstrated by a positive reaction to the Epstein-Barr virus latent-encoded membrane protein.