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目的:比较妥布霉素滴眼剂及注射剂在治疗细菌性角膜溃疡中的疗效。方法:选择确诊为细菌性角膜溃患者68例 (69只眼),随机分为甲组34例(34只眼)用妥布霉素滴眼液;乙组34例(35只眼)用妥布霉素注射液;比较两种给药途径的疗效。结果:甲组治愈率88．2％,有效率97．1％,无不良反应;乙组治愈率88．6％,有效率94．3％,不良反应发生1例。结论: 妥布霉素是一种有效的治疗细茵性角膜溃疡的药物。局部及全身治疗,疗效差异不显著,但局部给药不良反应发生率低,使用方便,患者痛苦小易于接受,使用滴眼液优于注射剂。
Objective: To compare the efficacy of tobramycin eye drops and injections in the treatment of bacterial corneal ulcer. Methods: Sixty-eight patients (69 eyes) diagnosed as bacterial corneal ulcer were randomly divided into three groups (34 eyes) with tobramycin eye drops and 34 cases (35 eyes) with group B Doxorubicin injection; compare the efficacy of the two routes of administration. Results: The cure rate of group A was 88.2%, the effective rate was 97.1%, no adverse reaction; the cure rate of group B was 88.6%, the effective rate was 94.3% and the adverse reaction occurred in 1 case. Conclusion: Tobramycin is an effective drug for the treatment of genital ulcer. Local and systemic treatment, the difference was not significant, but the incidence of adverse reactions to local administration is low, easy to use, patients suffering easy to accept the use of eye drops better than injection.