论文部分内容阅读
目的 :了解急性白血病患者血浆 s Fas水平及其意义。方法 :流式细胞仪免疫荧光双标法检测 71例急性白血病患者的血浆 s Fas含量 ,并与正常对照组比较。结果 :难治复发组急性白血病患者s Fas含量 (6 .2 3μg/ L± 1.31μg/ L;n=4 4 )显著高于 (P<0 .0 1)正常对照 (4 .85 μg/ L± 0 .92 μg/ L;n=2 8)和缓解组 (5 .12 μg/ L± 1.0 8μg/ L;n=2 7)。结论 :初步提示血浆 s Fas水平升高与急性白血病发生发展及细胞耐药有关
Objective: To understand the significance of plasma s Fas in patients with acute leukemia. Methods: Flow cytometry was used to detect the level of plasma s-Fas in 71 patients with acute leukemia by double-labeled immunofluorescence and compared with the normal control group. Results: The levels of sFas in relapsed patients with refractory relapse (6.23μg / L ± 1.31μg / L; n = 4 4) were significantly higher than those in normal control (4.85μg / L ± 0.92 μg / L; n = 2 8) and remission group (5.12 μg / L ± 1.0 8 μg / L; n = 2 7). Conclusion: It is suggested that elevated plasma s Fas level is associated with the occurrence and development of acute leukemia and cell resistance