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为了解医院经输血传播疾病的状况,于1991年3～11月份对郑州铁路局十四所医院用RPHA筛检HBsAg阴性后的献血员及待输血液用ELISA法、免疫酶技术,RPR法进行血清学监测。HB病原标志物监测标本118份,检出HBsAg16份,阳性率13.56%,HBeAg3份,阳性率2.54%,抗—HBc15份,阳性率9.65%,抗—HCV监测标本114份,检出11份,阳性率9.65%。HIV抗体,梅毒监测118份,结果均为阴性。根据本次监测结果说明:目前医院用RPHA筛检HBsAg阴性后的献血员及待输血液的感染HBV、HCV的情况,具有传染HB、HC的危险性。另外说明ELISA法检测HB病毒标示物较RPHA法敏感,并由此提出建议,医院应加强输血管理,创造条件开展灵敏的检测方法和项目,控制病毒性肝炎的发生。
In order to understand the condition of transfusion-transmitted diseases in hospitals, blood donors were screened by RPHA for HBsAg-negative blood donors and transfused blood at 14 hospitals in Zhengzhou Railway Bureau from March to November of 1991 by ELISA, immunoenzyme and RPR Serological surveillance. 118 HBsAg-positive samples were detected, the positive rate was 13.56%, HBeAg was 3, the positive rate was 2.54%, anti-HBc15, the positive rate was 9.65%, the anti-HCV surveillance samples were 114, 11 were detected, The positive rate of 9.65%. HIV antibody, 118 syphilis monitoring, the results were negative. According to this monitoring results show that: the current hospital with RPHA screening for HBsAg negative blood donors and blood transfusion infection HBV, HCV, with the risk of infection of HB, HC. In addition, the ELISA method is more sensitive than the RPHA method to detect the marker of HB virus. Therefore, the hospital should strengthen the blood transfusion management and create the conditions to carry out sensitive detection methods and projects to control the occurrence of viral hepatitis.