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近来发现,T 辅助细胞产生的淋巴因子在IgM 向IgG 亚类转换及IgE 的分泌过程中起重要作用。IL-4可诱导脂多糖(LPs)激活的鼠B 细胞分泌大量IgG1和IgE。同样,用IL-4培养的人类外周血单个核细胞
Recently, it has been found that lymphokines produced by T-helper cells play an important role in the conversion of IgM to IgG subclasses and the secretion of IgE. IL-4 induces lipopolysaccharide (LPs) -activated murine B cells to secrete large amounts of IgG1 and IgE. Similarly, human peripheral blood mononuclear cells cultured with IL-4