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用0～1.0GyX射线(剂量率:0.05Gy/min)全身一次性照射小白鼠后60天,观察小鼠精原细胞易位率,骨髓细胞和外周血淋巴细胞易位率。三类细胞易位率的剂量效应关系均为直线相关。淋巴细胞与骨髓细胞的效应曲线相近,曲线斜率(P>0.05)及总易位率(P>0.05)均无明显差异。精原细胞易位率曲线为骨髓细胞和淋巴细胞比斜率均有显著差异(P<0.05;P<0.01)。三类细胞总易位率比较,精原细胞易位率约是淋巴细胞的2.6倍,是骨髓细胞的2.2倍。本结果与大剂量照射的规律相反,其原因主要是小剂量照射时精原细胞死亡减少,染色体畸变丢失少,使生殖细胞易位率相对增加。
Sixty days after the whole body was irradiated with 0 ~ 1.0 Gy X-ray (dose rate: 0.05 Gy / min), the translocation rate of mouse spermatogonia and the translocation rate of bone marrow cells and peripheral blood lymphocytes were observed. The dose-response relationship of the three types of cell translocation rates are linear correlation. The effect curve of lymphocytes and bone marrow cells were similar. There was no significant difference between the slope of the curve (P> 0.05) and the total translocation rate (P> 0.05). The spermatogonial translocation rate curve showed a significant difference (P <0.05; P <0.01) in the ratio of bone marrow cells and lymphocytes. The total translocation rate of three types of cells, spermatogonial translocation rate of about 2.6 times the lymphocyte, 2.2 times that of bone marrow cells. The results with the law of high dose irradiation on the contrary, the main reason is that low doses of irradiation, sperm cell death decreased, less chromosomal aberrations lost so that the germ cell translocation rate increased.