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目的 探讨西比灵治疗椎基底动脉供血不足 (VBI)性眩晕的临床疗效。方法 选取椎基底动脉供血不足性眩晕的住院和门诊病例共 6 0例。随机抽取其中 30例为给西比灵治疗的治疗组 ,另 30例为给眩晕停治疗的双盲对照组。治疗后 3～ 6周复查经颅多普勒 (TCD) ,比较用药前后双椎、基底动脉的血流平均流速 (Vm)和收缩峰值 (Vs)的变化程度。结果 治疗组与对照组比较 ,3～ 6周复查TCD ,双椎、基底动脉的Vm ,Vs值改善程度有显著性差异 (P <0 0 1)。而对照组各血管的Vm ,Vs值变化程度差异无显著性 (P >0 0 5 )。结论 西比灵治疗椎基底动脉供血不足性眩晕疗效显著。
Objective To investigate the clinical effect of xipingling on vertigo of vertebrobasilar insufficiency (VBI). Methods A total of 60 inpatients and outpatients with vertigo of vertebrobasilar insufficiency were selected. Thirty patients were randomly selected as the treatment group for xibinger and the other 30 as double-blind control group for the treatment of dizziness. Transcranial Doppler (TCD) was performed at 3 to 6 weeks after treatment, and the changes of mean velocity (Vm) and peak (Vs) of blood flow in both vertebral and basilar arteries were compared before and after treatment. Results Compared with the control group, the improvement of Vm and Vs in the two vertebras and the basilar artery was significant (P <0.01). There was no significant difference in Vm and Vs between the control group and each group (P> 0.05). Conclusion Xibei Ling treatment of vertebrobasilar insufficiency vertigo significant effect.