从1993年12月至1995年8月对60例新生儿窒息患儿进行了血清VitE浓度的测定,并与100例正常新生儿作对照。结果发现窒息组血清VitE值比正常组显著下降。重度窒息与轻度窒息两组的血清VitE值无明显差异。而窒息时间与血清VitE值有关,窒息时间>5′组的血清VitE值低于<5′组。VitE是体内重要的抗氧化剂。窒息导致缺氯,而缺氧使产生大量自由基,抗氧化物的消耗增加。因此,新生儿窒息应考虑使用VitE治疗。 From December 1993 to August 1995, 60 cases of neonatal asphyxia were measured serum levels of VitE and compared with 100 normal newborns. The results showed that asphyxia serum VitE value decreased significantly than the normal group. There was no significant difference in serum VitE between severe asphyxia group and mild asphyxia group. Asphyxia time and serum VitE value, asphyxiation time> 5 ’group serum VitE value was lower than <5’ group. VitE is an important antioxidant in the body. Asphyxiation leads to lack of chlorine, and hypoxia causes a large number of free radicals, the consumption of antioxidants increased. Therefore, neonatal asphyxia should consider the use of VitE treatment.