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作者对２０例发病７２小时内的脑梗塞患者使用东菱克栓酶进行溶栓治疗。通过改良爱丁堡－斯堪的纳维亚评分法及脑循环动力学测定（ＣＶＡ）评价其作用。结果显示，用药后１、５、１０天与用药前比较，临床症状明显改善（Ｐ＜０．０５），梗塞侧ＣＶＡ参数中血流速度、血流量明显增加，尤其最小血流速度、最小血流量比较敏感。这说明用药后脑组织的低灌流状态得到了一定改善。本结果表明，ＤＦ－５２１的溶栓作用对脑梗塞急性期治疗有较大价值。
The author of 20 cases of onset within 72 hours of cerebral infarction patients using rhubarb bolt enzyme thrombolytic therapy. The effect was assessed by modified Edinburgh-Scandinavian scoring method and cerebral circulation kinetic assay (CVA). The results showed that after 1, 5, and 10 days of treatment, the clinical symptoms were significantly improved (P <0.05), the blood flow velocity and blood flow significantly increased in the infarct side CVA parameters, especially the minimum blood flow velocity and the minimum blood Traffic is more sensitive. This shows that after treatment of brain tissue hypoperfusion status has been a certain improvement. The results show that, DF-521 thrombolytic effect of acute cerebral infarction have great value.