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目的:了解万古霉素类的临床应用合理性及疗效情况。方法:采用回顾性调查方法,对2003年住院患者应用万古霉素类的药物利用率、疗效和合理性进行分析。结果:67份病历中万古霉素治疗有效率56.7%,不合理用药占44.3%。其中治疗用药58例(86.6%),预防用药9例(13.4%);经验用药的有效率和不合理用药比为52.2%,43.5%。结论:采取万古霉素类的药物使用限制措施,严格适应证,努力减少经验用药,有助于提高其疗效及合理用药水平。
Objective: To understand the clinical application of vancomycin rationality and efficacy. Methods: A retrospective survey was conducted to analyze the efficacy, efficacy and rationality of vancomycin inpatients in 2003. Results: The efficiency of vancomycin in 67 medical records was 56.7% and that of unreasonable medication was 44.3%. Among them, 58 cases (86.6%) were treated by medication and 9 cases (13.4%) were prophylactic medication. The effective and unreasonable dosage of empirical medication were 52.2% and 43.5% respectively. CONCLUSIONS: The adoption of vancomycin-containing drug use restrictions, strict indications, and efforts to reduce the experience of medication, help to improve its efficacy and reasonable drug levels.