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目的该课题旨在探讨糖尿病下肢神经病变患者应用马来酸桂哌齐特联合腺苷钴胺治疗的临床效果。方法通过随机数字法的分组方法将该院2015年4月-2017年8月在院治疗的糖尿病下肢神经病变患者112例分配到试验组和对照组。试验组56例患者采用马来酸桂哌齐特联合腺苷钴胺治疗,对照组56例采用常规治疗,对比两组临床指标与总有效率。结果试验组糖尿病下肢神经病变患者SNCV与MNCV测量值高于对照组,总有效率高于对照组,均差异有统计学意义(P<0.05)。结论糖尿病下肢神经病变患者的总有效率可通过马来酸桂哌齐特联合腺苷钴胺治疗显著提高,临床指标能够得到明显改善,值得推广。
Objective To explore the clinical effect of cinepazide maleate combined with adenosylcobalamin in patients with diabetic lower extremity neuropathy. Methods 112 patients with diabetic lower extremity neuropathy treated in our hospital from April 2015 to August 2017 in our hospital were assigned to the experimental group and the control group by random number method. Fifty-six patients in trial group were treated with cinepazide maleate combined with adenosylcobalamin, and 56 patients in control group were treated by conventional therapy. The clinical indexes and total effective rate were compared between the two groups. Results The SNCV and MNCV in patients with diabetic lower extremity neuropathy in the experimental group were higher than those in the control group, and the total effective rate was higher than that in the control group (P <0.05). Conclusion The total effective rate of patients with diabetic lower extremity neuropathy can be significantly improved by the combination of cinepazide maleate and adenosylcobalamin, and the clinical indexes can be significantly improved and worthy of promotion.