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黄芪是传统补益中药,为补药之长,《神农本草经》列之为“上品”。近年来,对黄芪的生药学、化学、药理及临床应用等方面做了大量研究,黄芪的作用机理得到进一步的阐明。现就黄芪1997～1998年的研究进展分述如下: 1 药理研究 1.1 提高免疫力 黄芪对T淋巴细胞亚群比例有调节作用,其机制可能为黄芪对肝细胞核代谢的直接作用,保护细胞内质网,使肝细胞内粗面内质网增加,即增加了细胞内rRNA和mRNA的含量,抑制核糖核激酶活性及增加核糖核激酶抑制因子的活性,也可能是通过抑制Ts细胞而促进机体的免疫反应。赵氏等认为,黄芪明显促进植物血凝素(PHA)诱导的外周单个核细胞(PBMC)产生IFN-γ及PWM诱导的PBMC
Astragalus is a traditional tonic medicine, is the tonic for the long, “Shen Nong’s Herbal Classic” listed as “top grade.” In recent years, the pharmacology, chemistry, pharmacology and clinical application of Astragalus have done a lot of research, the mechanism of Astragalus further clarification. Astragalus 1997 to 1998 now on the progress of the research are described below: 1 pharmacological studies 1.1 to enhance immunity Astragalus on T lymphocyte subsets have a regulatory role, the mechanism may be the direct effect of Astragalus on liver cell nuclear metabolism and protect the endoplasmic reticulum Network, so that increased intrahepatic endoplasmic reticulum in liver cells, that is, increase the content of intracellular rRNA and mRNA, inhibit ribozyme activity and increase the activity of ribonuclease inhibitor, may also be through the inhibition of Ts cells and promote the body immune response. Zhao et al., That Astragalus significantly promote phytohemagglutinin (PHA) -induced peripheral mononuclear cells (PBMC) to produce IFN-γ and PWM-induced PBMC