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目的对糖尿病足感染作出综合评价,争取做到早期预防及系统合理的治疗。方法对72例糖尿病足感染患者溃疡处细菌培养所获病原菌情况及相关用药情况进行回顾性分析。结果72例糖尿病足感染患者中45例患者溃疡处分离出62株病原菌,排列前3位者为金黄色葡萄球菌(20.97%),表皮葡萄球菌(19.35%),大肠埃希菌(16.13%)。45例患者使用抗菌药物133例次,以杀菌性β-内酰胺抗生素为主,占51.88%(69/133),44.36%(59/133)的患者使用了抗厌氧菌药物。结论糖尿病足感染多为混合性感染,其致病菌多为多重耐药,金黄色葡萄球菌为最常见病原菌。应结合糖尿病足感染的临床特征,根据药敏结果选择有效抗菌药物,防止滥用抗生素和耐药菌株的出现,提高治愈率。
Objective To make a comprehensive assessment of diabetic foot infection, strive for early prevention and systematic treatment. Methods A retrospective analysis was made on the pathogenic bacteria in the ulcer of 72 patients with diabetic foot infection and related medication. Results Totally 62 pathogenic bacteria were isolated from 45 patients with diabetic foot infection. Staphylococcus aureus (20.97%), Staphylococcus epidermidis (19.35%), Escherichia coli (16.13%), . Forty-five patients were treated with antimicrobial drugs for 133 times, with bactericidal β-lactam antibiotics as the main drug, accounting for 51.88% (69/133) and 44.36% (59/133) of patients with anti-anaerobic drugs. Conclusion Most of diabetic foot infections are mixed infections, and the pathogens are mostly multi-drug resistant. Staphylococcus aureus is the most common pathogen. Should be combined with the clinical features of diabetic foot infection, drug susceptibility results based on the selection of effective antimicrobial agents to prevent the abuse of antibiotics and drug resistant strains appear to improve the cure rate.