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急性冠脉综合征(ACS)的诊断主要依赖于临床表现、心电图和血生化标记物。目前临床上应用的血生化标记物(如心肌肌钙蛋白、肌红蛋白和心肌型肌酸激酶同工酶等)均在组织已发生坏死后才释放入血;而研究发现缺血修饰白蛋白能在ACS的早期可逆阶段检出,具有极高的灵敏度,有助于ACS的除外诊断及短期危险分层和预后。
The diagnosis of acute coronary syndrome (ACS) depends mainly on clinical manifestations, electrocardiogram and blood biochemical markers. At present, blood biochemical markers (such as cardiac troponin, myoglobin and cardiac muscle creatine kinase isoenzyme) in clinical application are released into the blood after the tissue has been necrotic. However, it has been found that ischemia-modified albumin Can be detected in the early reversible ACS phase, with high sensitivity, contribute to the exclusion of ACS diagnosis and short-term risk stratification and prognosis.