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华蟾素注射液是我国自行研制开发的二类新药,是由中华大蟾蜍Bufo bufo gargarizans皮提取的主要成分经加工制成的水溶性制剂,具有良好的抗肿瘤作用,是我国临床中应用较广的抗肿瘤药物,尤其对肝癌的效果较好。其不仅对多种肝癌细胞有杀伤和抑制作用,而且许多临床医生发现华蟾素单用及联合介入治疗等手段治疗肝癌均收到良好的效果。对华蟾素抗肝癌的基础和临床最新研究进行综述,为进一步开发和应用提供参考。
Cinobufotalin Injection is a new type of new drug developed and developed by our country. It is a water-soluble preparation made by processing the main components extracted from Bufo bufo gargarizans skin of Chinese Bufo bufo gargarizans and has good anti-tumor effect. Wide anti-tumor drugs, especially for liver cancer better. It not only has a variety of liver cancer cell killing and inhibition, and many clinicians found that cinobufotalin alone and combined interventions and other means of treatment of liver cancer have received good results. This review summarizes the basic and clinical researches on anti-hepatocellular carcinoma of cinobufacini and provides reference for further development and application.