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报道合成新型磷酸二酯酶5 型(PDE5) 抑制剂昔多芬(sildenafil) 的新方法.本方法设计的合成路线步骤少、反应时间短、无昂贵试剂.总收率为27-3 % .
A new method of synthesizing sildenafil, a novel phosphodiesterase type 5 (PDE5) inhibitor, was reported. This method is designed synthesis route less steps, short reaction time, no expensive reagents. The total yield is 27-3%.