目的:分析小儿脊髓压迫症(SCC)的病因及其临床特点，为临床提供参考。方法:对2014年1月至2019年8月苏州大学附属儿童医院收治的36例SCC患儿进行随访研究，分析其临床特点、诊疗方法、疗效及其预后情况。结果:36例患儿中，男15例，女21例，平均年龄79.6(1～169)个月，随访中位时间6(2～47)个月。临床表现多样，包括运动功能受累23例(63.89%)、感觉异常6例(16.67%)、括约肌功能障碍10例(27.78%)、局部疼痛14例(38.89%)。根据美国脊柱损伤协会Frankel分级标准，36例起病时脊髓损伤程度：A级2例(5.56%)、B级2例(5.56%)、C级10例(27.78%)、D级14例(38.89%)，E级8例(22.22%)。主要治疗措施为糖皮质激素应用、椎管减压术、原发瘤灶切除术及后续康复、化疗等，28例(77.78%)脊髓功能经治疗后基本恢复，另外8例中，1例死亡，1例失访，其他6例患儿脊髓功能无明显改善甚至恶化。生存分析提示良性占位所致SCC患儿中发病时脊髓损伤程度较轻(Frankel分级D～E级) (n P＝0.017)、治疗间隔4周以内者(n P＝0.030)恢复较好，外伤所致SCC患儿中病初运动功能受累者恢复不佳(n P＝0.025)。n 结论:Frankel分级提示起病时脊髓损伤程度较重、运动功能受累，治疗间隔较长在不同病因的SCC患者中可能提示远期脊髓功能恢复不佳。“,”Objective:To analyze the etiology, clinical characteristics and prognosis of children suffering from spinal cord compression (SCC), so as to provide reference for clinic.Methods:A total of 36 SCC children who were admitted to Children′s Hospital Affiliated to Soochow University from January 2014 to August 2019 were followed up.The relationship among clinical characteristics, diagnosis, treatment and curative effect was analyzed.Results:Among the 36 children, with 15 males and 21 females, the average age was 79.6 (1-169) months, and the median follow-up time was 6 (2-47) months.Clinical manifestations were various, with 23 cases (63.89%) with motor function, 6 cases (16.67%) with sensory abnormality, 10 cases (27.78%) with sphincter dysfunction, and 14 cases (38.89%) with pain.According to Frankel Classification Standard of the American Spinal Injury Association, the degree of spinal cord injury at onset was as follows: grade A in 2 cases (5.56%), grade B in 2 cases (5.56%), grade C in 10 cases (27.78%), grade D in 14 cases (38.89%) and grade E in 8 cases (22.22%). The main therapeutic measures for all children were the application of glucocorticoid, spinal canal decompression, resection of primary tumor and subsequent rehabilitation and chemotherapy.The spinal cord function of 28 cases (77.78%) began to improve gradually after the treatment.Among other 8 cases, 1 case died, 1 case lost follow-up, and the other 6 cases had no significant improvement or even suffered from the deterioration of spinal cord function.n Kaplan-n Meier analysis proved that patients with milder spinal cord injury (Frankel grading standard, grade D-E) (n P=0.017) and shorter treatment interval (n P=0.030) in benign mass group would have better outcomes.Children without motor dysfunction in trauma induced SCC group also recovered better (n P=0.025).n Conclusions:The severity of spinal cord injury based on Frankel classification, motor dysfunction, and longer treatment interval may indicate poor recovery of spinal cord function in SCC patients with different etiologies.