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目的:探讨2型糖尿病(T2DM)合并非酒精性脂肪肝(NAFLD)与血脂紊乱的关系。方法:对74例T2DM合并NAFLD患者进行体质指数(BMI)、糖化血红蛋白(HbA1c)、TG、TC、LDL、HDL Lp(α)、apoA和apoB的测定,并与40例非脂肪肝糖尿病患者作比较。结果:脂肪肝组BMI、HbA1c、TG、TC、LDL和apoB水平均较非脂肪肝组明显升高(P<0.05～0.01),HDL、apoA和Lp(α)水平无明显差异(P>0.05)。结论:T2DM合并NAFLD较未并发脂肪肝患者存在明显的脂质代谢异常及血糖异常,提示合并脂肪肝的T2DM具有更多的冠心病危险因素。
Objective: To investigate the relationship between type 2 diabetes mellitus (T2DM) with non-alcoholic fatty liver disease (NAFLD) and dyslipidemia. Methods: The body mass index (BMI), HbA1c, TG, TC, LDL, HDL Lp (α), apoA and apoB were measured in 74 T2DM patients with NAFLD and compared with 40 patients with non-steatohepatitis Compare Results: The levels of BMI, HbA1c, TG, TC, LDL and apoB in steatosis group were significantly higher than those in steatosis group (P <0.05-0.01), but there was no significant difference in HDL, apoA and Lp ). Conclusion: T2DM with NAFLD has significantly abnormal lipid metabolism and abnormal blood glucose in patients with non-concurrent fatty liver, suggesting that T2DM with fatty liver has more risk factors for coronary heart disease.