论文部分内容阅读
目的分析婴幼儿轮状病毒肠炎疗效的影响因素。方法 2014年10月-2016年2月,医院共收治住院婴幼儿轮状病毒肠炎患儿78例,给予个体化治疗,以抗病毒+补液治疗+对症治疗为主,选择性应用胃肠道黏膜保护剂、微生态制剂、锌剂、中药治疗,将痊愈患儿与未痊愈患儿进行对比分析,分析婴幼儿轮状病毒肠炎疗效的影响因素。结果痊愈40例,痊愈患儿与未痊愈患儿在重度、锌剂、蒙脱石散、微生态制剂等因素差异均有统计学意义(P<0.05),但在男性、年龄>12个月、早产儿、既往有腹泻病史、入院前接受过治疗、发热、中西医结合等因素差异无统计学意义(P>0.05);多因素Logistic回归分析结果示,重度[OR=0.625,95%CI(1.560~2.455)]、锌剂[OR=1.141,95%CI(1.301~5.240)]成为痊愈的独立影响因素,差异具有统计学意义(P<0.05)。结论轮状病毒肠炎患儿的疗效差别较大,疗效与疾病严重程度、治疗方法有关。
Objective To analyze the influencing factors of infantile rotavirus enteritis. Methods From October 2014 to February 2016, 78 children with infantile rotavirus enteritis were admitted to the hospital. Individualized treatment was given. Antiviral therapy, rehydration therapy and symptomatic treatment were used. Selective gastrointestinal mucosa Protective agents, probiotics, zinc agents, traditional Chinese medicine treatment of children will be recovered and uncomplicated children were analyzed and compared, analysis of infant and child rotavirus enteritis efficacy factors. The results were cured in 40 cases. There were significant differences in severe, zinc agent, montmorillonite powder, probiotics and other factors between children with and without recovery (P <0.05), but in males> 12 months (P> 0.05). The results of multivariate logistic regression analysis showed that severe [OR = 0.625, 95% CI (1.560 ~ 2.455), zinc (OR = 1.141,95% CI 1.301-5.240) were independent factors of recovery. The difference was statistically significant (P <0.05). Conclusions The therapeutic effect of rotavirus enteritis is quite different. The curative effect is related to the severity of the disease and treatment.