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用人参养荣汤和低剂量的强的松龙从6周龄始给MRL/1 小鼠灌胃,每周5次,观察到此联合疗法能显著延长MRL/1小鼠的生存期,并降低外周血中抗ds-DNA 自身抗体和免疫复合物水平。流式细胞分析结果表明:联合治疗能显著减少淋巴器官中异常B220~+T 细胞数并可能由此增强脾细胞和淋巴结细胞对丝裂原的反应.
The MRL/1 mice were intragastrically administered from 6 weeks old with ginseng Rongrong decoction and low dose Prednisolone, 5 times per week, and the combination therapy was observed to significantly prolong the survival of MRL/1 mice. Reduce the level of anti-ds-DNA autoantibodies and immune complexes in peripheral blood. Flow cytometric analysis showed that combination therapy significantly reduced the number of abnormal B220~+ T cells in lymphoid organs and may thus increase the response of splenocytes and lymph node cells to mitogen.