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目的评估复方苦参注射液治疗恶性肿瘤癌性疼痛的临床效果。方法选取2010年2月~2013年4月间湖北省黄冈市中心医院进行治疗的恶性肿瘤患者100例为研究对象进行回顾性分析;根据随机数字表随机均分为对照组(n=50)和研究组(n=50)。在接受常规治疗的基础上,对照组加用三阶梯止痛法,研究组加用复方苦参注射液;采用疼痛数学评估法(numerical rating scale,NRS)评估2组患者治疗前后的疼痛状况并进行对比;同时用Karnofsky评分法评估2组患者治疗前后的生活质量评分并进行对比。结果研究组治疗疼痛的效果好于对照组,差异具有统计学意义(P<0.05);研究组生活质量评分优于对照组的,差异具有统计学意义(P<0.05)。结论复方苦参注射液治疗恶性肿瘤癌性疼痛的临床疗效较好,且能够显著改善患者生活质量。
Objective To evaluate the clinical effect of Compound Kushen Injection in the treatment of malignant tumor. Methods A total of 100 patients with malignant tumors treated in Huanggang Central Hospital from February 2010 to April 2013 were retrospectively analyzed. According to random number table, they were randomly divided into control group (n = 50) and control group Study group (n = 50). On the basis of routine treatment, three-step analgesia was used in the control group, and compound Kushen injection was used in the study group. The pain status before and after treatment was evaluated by using the numerical rating scale (NRS) The Karnofsky score was used to evaluate the quality of life before and after treatment in two groups and compared. Results The study group was better than the control group in the treatment of pain, the difference was statistically significant (P <0.05). The quality of life score of the study group was better than that of the control group (P <0.05). Conclusion Compound Kushen injection for the treatment of malignant tumor with good clinical curative effect, and can significantly improve the quality of life of patients.