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目的研究百尾参Disporum cantoniense的化学成分。方法利用各种色谱技术进行分离,运用现代光谱技术鉴定化合物结构。结果从百尾参中分离得到16个化合物,分别鉴定为马来酸酰亚胺-5-肟(1)、4-methylene-5-oxopyrrolidine-2-carboxylic acid(2)、胸腺嘧啶(3)、腺嘌呤核苷(4)、5′-deoxy-5′-methylamino-adenosine(5)、乙基-α-L-鼠李糖(6)、岩白菜素(7)、4-羟基-2-甲氧基苯基-6-脱氧-α-L-吡喃木糖苷(8)、(-)-表儿茶素(9)、(6R,9R)-roseoside(10)、3-(4-羟基-3,5-二甲氧基苯基)-丙烷-1,2-二醇(11)、3-羟基-5-(p-羟基苯基)-戊酸(12)、1-核糖醇基-2,3-二酮-1,2,3,4-四氢-6,7-二甲基-喹喔啉(13)、(6S,9R)-vomifoliol(14)、3,4-二羟基苯酰甲醇(15)和1,2-二羟基-1-(4-羟基-3,5-二甲基苯基)-乙烷(16)。结论化合物1、2、5~9、12~16为首次从该属植物中分离得到;化合物1、2、5~10、12~16为首次从该植物中分离得到。
Objective To study the chemical constituents of Disporum cantoniense. The method uses a variety of chromatographic techniques for separation and the use of modern spectroscopic techniques to identify compounds. Results Sixteen compounds were isolated and identified as 4-methylene-5-oxopyrrolidine-2-carboxylic acid (2), thymine (3) , Adenosine (4), 5’-deoxy-5’-methylamino-adenosine (5), ethyl-aL- rhamnose - (-) - epicatechin (9), (6R, 9R) -roseoside (10), 3- 3,5-dimethoxyphenyl) -propane-1,2-diol (11), 3-hydroxy-5- (p- hydroxyphenyl) -pentanoic acid (12) 2,3-dione-1,2,3,4-tetrahydro-6,7-dimethyl-quinoxaline (13), (6S, 9R) -vomifoliol (14) Dihydroxybenzyl alcohol (15) and 1,2-dihydroxy-1- (4-hydroxy-3,5-dimethylphenyl) -ethane (16). Conclusions Compounds 1, 2, 5 ~ 9 and 12 ~ 16 were isolated from this genus for the first time. Compounds 1, 2, 5 ~ 10 and 12 ~ 16 were isolated from this plant for the first time.