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目的:探讨2型糖尿病(T2DM)患者空腹血糖与血脂水平的相关性。方法:选取2015年1月在佛山市第一人民医院禅城医院接受体检的T2DM患者99例与健康个体的空腹血糖101例的血脂检测结果进行回顾性分析,比较两组间的差异。结果:健康组和糖尿病组空腹血糖(FPG)与总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)均存在相关性;在健康组,FPG与LDL-C呈负相关(-0.4001);而在糖尿病组,FPG与LDL-C呈正相关(0.08456);另外,逐步回归分析显示:FPG是高TG血症的风险因素(R2=0.079),是LDL-C减低的风险因素(R2=0.091)(P<0.05)。结论:空腹血糖较高T2DM患者,LDL-C、TC和TG升高,而HDL-C减低,应予调脂治疗,以减少心血管疾病的发生率。
Objective: To investigate the relationship between fasting blood glucose (FBG) and serum lipids in type 2 diabetes mellitus (T2DM). Methods: A retrospective analysis of blood lipids in 99 patients with T2DM and 101 patients with fasting plasma glucose in Chancheng Hospital of Foshan City in January 2015 was conducted to compare the differences between the two groups. Results: Fasting plasma glucose (FPG), total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C) In the healthy group, there was a negative correlation between FPG and LDL-C (-0.4001). In diabetic group, FPG was positively correlated with LDL-C (0.08456). In addition, stepwise regression analysis showed that FPG was associated with a high risk of TG Factor (R2 = 0.079) was a risk factor for LDL-C reduction (R2 = 0.091) (P <0.05). CONCLUSION: LDL-C, TC and TG are elevated in patients with high fasting plasma glucose (T2DM), while HDL-C is decreased. Lipid-lowering therapy should be given to reduce the incidence of cardiovascular disease.