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【目的】探讨2型糖尿病（T2DM ）患者尿白蛋白排泄量与视网膜病变（DR）的相关性。【方法】260例T2DM患者，依据尿白蛋白排泄量分为正常白蛋白尿组41例（NA组，24 h尿白蛋白＜30 mg）、微量白蛋白尿组118例（M A U组，24 h尿白蛋白30～300 m g ）和大量白蛋白尿组101例（C A U组，24 h尿白蛋白＞300 mg）。检测各组患者的24 h尿白蛋白定量并进行眼底检查，分析T2DM患者尿白蛋白排泄量与DR的相关性。【结果】NA组单纯性视网膜病变（NPDR）检出率为98．％，增殖性视网膜病变（PDR）检出率为48．％；MAU组NPDR检出率为43．2％，PDR检出率为16．1％；CAU 组 NPDR检出率为42．6％，PDR检出率为347．％；各组NPDR和PDR检出率比较差异有统计学意义（ P ＜00．5）；相关性分析结果显示，T2DM 患者尿白蛋白排泄量与DR检出率呈正相关（ P ＜00．5）。【结论】T2DM 患者尿白蛋白排泄量与DR的发生显著相关，两者可能存在共同的病理生理基础。“,”[Objective] To analyze the relationship between urinary albumin excretion and diabetic retinop‐athy in type 2 diabetics mellitus .[Methods] Two hundred and sixty patients with type 2 diabetics mellitus were divided into normal albuminuria group(NA ,n = 41 ,24h‐urinary albumin≤30mg) ,microalbuminuria group (MAU ,n =118 ,30mg<24h‐urinary albumin<300mg) and macroalbuminuria group(CAU ,n =101 , 24h‐urinary albumin≥300mg) .All the patients were measured in terms of 24h‐urinary albumin and examined by digital retinal photographs ,thus the relationship between urinary albumin excretion and diabetic retinopathy in type 2 diabetics can be analyzed .[Results] The non proliferative diabetic retinopathy (NPDR) detection rate in the NA group was 9 8.% ,and the detection rate of proliferative diabetic retinopathy (PDR) was 4 8.% ;The detection rate of NPDR in the MAU group was 43 2.% ,and the detection rate of PDR was 16 1.% ;The detec‐tion rate of NPDR in the CAU group was 42 6.% ,and the detection rate of PDR was 34 7.% ;There were sig‐nificant differences in the detection rates of NPDR and PDR in each group ( P <0 0.5);Correlation analysis showed that urinary albumin excretion rate was positively correlated with the rate of DR in T2DM patients ( P<0 0.5)[.Conclusion] The urinary albumin excretion rate of T2DM patients is significantly correlated with the occurrence of DR .The above factors may have a common pathophysiological basis .