Survival and an overview of decision-making in patients with cholangiocarcinoma

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BACKGROUND:?Cholangiocarcinoma is rare, accounting for approximately 3%of all gastrointestinal cancers. This study aimed to identify the survival rate among surgically treated and palliated patients, and secondly to identify parameters that could predict a curative resection. METHODS:?A total of 121 patients, 55 men and 66 women, median age 70 years (range 31-91), who had been treated for cholangiocarcinoma in the period of 1990-2005 were evaluated retrospectively. RESULTS:?Curative resection was performed in 40 patients (33%), whereas 81 received palliative treatment (67%). 16%(19 of 121) of the patients had an explorative laparotomy without tumour resection. Age above 65 years (OR 3.4;95%CI 1.4-8.4;P=0.008), weight loss (OR 8.5;95%CI 1.5-46;P=0.01) or tumour location (The resection rate of hilar cholangiocarcinoma was lower than that of intrapancreatic cancer.) (OR 2.7; 95% CI 1.7-4.5; P=0.001) predicted palliative treatment. The adjusted 5-year survival rate of patients who received tumour resection and palliative treatment was 30%and 1.2%, respectively (P
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