DNA疫苗作为疫苗研制工业中的新成果已经得到了越来越多得关注。为了提高其免疫原性,发挥它最大的保护作用,人们进行了各种尝试。近几年来的研究表明,通过密码子优化的方式可以提高DNA疫苗的免疫原性,增强其免疫保护作用。本文即针对该问题做了一些总结。 DNA vaccines, as a new achievement in the vaccine development industry, have received increasing attention. In order to improve its immunogenicity, to play its greatest protective effect, people have made various attempts. In recent years, studies have shown that, by codon optimization approach can improve the immunogenicity of DNA vaccines and enhance their immune protection. This article is to do some summary of the problem.