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目的 了解疑似脑膜炎患儿脑脊液改变程度与其临床表现的关系。 方法 将纳入细菌性脑膜炎监测系统疑似脑膜炎病例根据脑脊液改变的程度分成 3组 ,统计其临床表现 ,并进行流行病学统计、分析。 结果 3组病例均以≤ 2 4月龄段为主 ,尤以CSF培养阳性组为高 ,男性发病的比例高于女性 ;除抽搐外 ,临床表现普遍有CSF培养阳性组高于异常组 ,异常组高于正常组的特点 ;≤ 2 4月龄段患儿囟门膨突的构成比高于 2 5～ 36月龄段 ,而≥ 3项临床表现的构成比后者则高于前者 ;异常组女性的囟门膨突的构成比高于男性 ;≥ 3项临床表现以异常组及CSF培养阳性组的夏季为最高 ;农村患儿临床表现构成比高于城市患儿 ;采样前不用抗菌素者抽搐的构成比高于采样前使用抗菌素者 ,但总的来说两种情况患儿的临床表现差异并不明显。 结论 CSF改变程度与临床表现的关系呈正相关 ,抽搐不是脑膜炎特异性的表现 ,对于农村患儿、女性患儿尤其在夏季特别要注意护理和治疗
Objective To investigate the relationship between cerebrospinal fluid (CSF) changes and clinical manifestations in children with suspected meningitis. Methods The cases of suspected meningitis included in the monitoring system of bacterial meningitis were divided into 3 groups based on the degree of cerebrospinal fluid changes. The clinical manifestations were statistically analyzed and statistically analyzed. Results Most of the patients in the three groups were ≤2 4 months old, especially in the positive CSF culture group. The incidence of male patients was higher than that of the female ones. In addition to convulsions, the CSF clinical manifestations were generally higher than those in the abnormal group and abnormal group Group was higher than the normal group. The incidence ratio of fontanel of bullae in children younger than 24 months was higher than that of 25 ~ 36 months old group, while the clinical manifestations of ≥3 items were higher than those of the former group. The abnormal group The composition ratio of fontanelle protrusion was higher in females than in males; ≥3 clinical manifestations were the highest in summer in abnormal group and CSF positive group; the clinical manifestation ratio in rural children was higher than that in urban children; twitch without antibiotic before sampling The composition ratio is higher than that of the sample before the use of antibiotics, but in general the difference between the two clinical manifestations of children is not obvious. Conclusions There is a positive correlation between the degree of CSF change and clinical manifestations. Convulsion is not a specific manifestation of meningitis. In rural children, especially in the summer, women should pay special attention to nursing and treatment