采用国产安吖啶（ｍ－ａｍｓａｃｒｉｎｅ，ＡＭＳＡ）联合方案治疗急性白血病（ＡＬ）３０例；急性淋巴细胞白血病（ＡＬＬ）６例，急性非淋巴细胞白血病（ＡＮＬＬ）２４例；初治２１例，复治９例。总的ＣＲ率为７６．７％；ＡＬＬ的ＣＲ率为６６．６％，ＡＮＬＬ的ＣＲ率为７９．２％，初、复治病例的ＣＲ率分别为８０．９％、６６．７％。主要毒性为骨髓抑制，其次为脱发、食欲下降、恶心、呕吐、口腔粘膜炎、静脉炎等。 A total of 30 cases of acute leukemia (AL) were treated with a domestic m-amsacrine (AMSA) combination regimen; 6 cases of acute lymphoblastic leukemia (ALL) and 24 cases of acute nonlymphocytic leukemia (ANLL); 21 cases were initially treated. Treatment of 9 cases. The overall CR rate was 76.7%; the CR rate for ALL was 66.6%, the CR rate for ANLL was 79.2%, and the CR rates for primary and retreatment cases were 80.9% and 66.7%, respectively. The main toxicity was bone marrow suppression, followed by hair loss, loss of appetite, nausea, vomiting, oral mucositis, and phlebitis.