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目的分析影响肝性脑病预后的相关因素,评价判断预后因素的标准,探讨其临床适用性。方法选择2009年5月-2012年8月于我院就诊的43例肝硬化合并肝性脑病的住院患者,将确诊为肝性脑病的日期作为时间起点基线,选择13个可能对肝性脑病预后产生影响的相关指标,通过Cox比例风险模型对患者的预后进行评估,同时筛选出几个独立影响预后因素。结果经Cox回归分析,筛选出4个肝性脑病的独立影响预后因素。结论应用Cox回归可以较为便捷地判断影响预后因素,上消化道出血、电解质紊乱、放腹水、感染、手术、利尿剂及肝功能分级为影响肝性脑病预后的独立因素。
Objective To analyze the related factors that affect the prognosis of hepatic encephalopathy and evaluate the criteria for judging the prognostic factors and to explore its clinical applicability. Methods Forty-three inpatients with cirrhosis and hepatic encephalopathy who were treated in our hospital from May 2009 to August 2012 were enrolled in this study. The date of diagnosis of hepatic encephalopathy was taken as the baseline of the starting point of time. Thirteen patients who were selected for their prognosis of hepatic encephalopathy Related indicators of impact, through the Cox proportional hazards model to assess the prognosis of patients, while screening out several independent prognostic factors. Results By Cox regression analysis, four independent prognostic factors of hepatic encephalopathy were screened out. Conclusions Cox regression can be used as an independent factor to predict the prognosis of hepatic encephalopathy by analyzing the prognostic factors, upper gastrointestinal bleeding, electrolyte imbalance, ascites, infection, surgery, diuretic and liver function classification.