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目的 了解SARS在医务人员中感染状况、抗体检测、临床和预后等特点。方法 对该院2月份感染SARS的20名医务人员的流行病学及临床资料进行回顾性分析及抗体检测、肺功能检查。结果 20名医务人员感染者中,男4例,女16例;医生8例,护士12例,平均年龄(26.8±6.0)岁;医务人员感染SARS的潜伏期是1～13d,常见潜伏期是2～6 d(14例),平均潜伏期(3.6±1.3)d,平均住院时间(26.1±11.5)d;该院一线工作人员231人,医务人员的感染率是8.7％(20/231),治愈率是100％,无一例死亡。由于消毒隔离防护措施得当,最近3个多月以来,该院未再有医务人员感染SARS。跟踪调查显示,20例医护人员预后良好,目前已全部恢复临床一线工作;19/20例(95.0％)肺功能检测完全恢复正常,1例通气功能轻度异常;抗体检测90.0％恢复期SARS抗体阳性,双份血清5/6例恢复期SARS抗体滴度升高,4/60例未感染一线人员抗体阳性。结论 医务人员感染SARS的流行病学、临床特点与一般SARS患者基本相同,我院医务人员的SARS感染率较低,临床治愈率高,追踪3个多月大多预后良好。目前的SARS抗体检测可以诊断大部分SARS患者,SARS存在隐性感染的可能。
Objective To understand the SARS infection in medical staff, antibody testing, clinical and prognosis characteristics. Methods The epidemiological and clinical data of 20 medical workers infected with SARS in the hospital in February were retrospectively analyzed, as well as antibody test and pulmonary function test. Results There were 4 males and 16 females in 20 medical staffs, 8 were doctors and 12 were nurses, with an average age of (26.8 ± 6.0) years. The incubation period for medical staff was 1 ~ 13 days and the common incubation period was 2 ~ The average incubation period was (3.6 ± 1.3) d, average length of stay was (26.1 ± 11.5) days. There were 231 hospital staff in the hospital and the infection rate of medical staff was 8.7% (20/231). The cure rate Is 100%, no one died. Due to the proper disinfection and isolation protection measures, no medical staff have been infected with SARS in the hospital for more than three months. The follow-up survey showed that 20 medical staffs have a good prognosis, and all the patients have recovered to the first-line work at present. Pulmonary function tests returned to normal in 19/20 (95.0%) patients and mild dysfunction in ventilation patients. Antibody was detected 90% recovery SARS antibody Positive, double serum 5/6 convalescent SARS antibody titers increased, 4/60 uninfected front-line staff antibody positive. Conclusions The epidemiology and clinical features of SARS among medical staff are basically the same as those of SARS patients. The SARS infection rate of medical staff in our hospital is low, and the clinical cure rate is high. Most of the follow-up of more than 3 months has a good prognosis. The current SARS antibody test can diagnose most patients with SARS, SARS there is the possibility of latent infection.