论文部分内容阅读
目的分析2010—2014年湖州市预防接种后过敏性皮疹的发生特征,为规范疫苗接种后过敏性皮疹报告和诊断提供参考。方法收集湖州市2010—2014年“国家疑似预防接种反应信息管理系统”中诊断为过敏性皮疹的个案资料及数据,采用描述性流行病学方法进行分析。结果 2010—2014年湖州市共报告过敏性皮疹97例,报告发生率为2.11/10万剂;年均报告发生率安吉县最高且高于全市平均水平,长兴县最低且低于全市平均水平;第三季度报告数占42.26%,男女性别比为1.06∶1;<1岁儿童占60.82%;发生于接种第一剂占85.57%;过敏性皮疹发生在接种当天的占58.76%;报告发生率居前3位的疫苗是百白破IPV和Hib五联疫苗(28.60/10万剂)、麻风疫苗(26.41/10万剂)和麻腮疫苗(21.98/10万剂)。结论需加强过敏性皮疹的鉴别诊断和调整诊断分类,并对部分报告发生率较高的疫苗做进一步分析研究。
Objective To analyze the incidence of allergic skin rash after vaccination in Huzhou during 2010-2014, and to provide reference for standardizing the report and diagnosis of allergic skin rash after vaccination. Methods The data and data of cases diagnosed as allergic rash in 2010-2014 National Suspected Vaccination Response Information Management System were collected and analyzed by descriptive epidemiological method. Results A total of 97 cases of allergic skin rash were reported in Huzhou from 2010 to 2014, with a reported incidence of 2.11 / 10 million doses. The average annual incidence was reported to be the highest in Anji County and higher than the average level in the city, the lowest in Changxing County and lower than the city average. The number of reports in the third quarter accounted for 42.26%, the sex ratio of men and women was 1.06:1; children <1 year old accounted for 60.82%; those who took the first dose accounted for 85.57%; allergic rash occurred 58.76% on the day of inoculation; The top 3 vaccines were diphtheria-IPV and Hib pentavalent (28.60 / 100,000), leprosy (26.41 / 100,000) and mumps vaccine (21.98 / 100,000). Conclusion It is necessary to strengthen the differential diagnosis of allergic rash and adjust the diagnosis of classification, and some of the higher incidence of vaccine reports for further analysis.