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目的原发性食管淋巴上皮瘤样癌罕见,本文旨在探讨该病的组织病理学特点,以及其与EB病毒的关系,以增强对本病的认识。方法回顾性分析1例原发性食管淋巴上皮瘤样癌的临床资料,并复习相关文献进行讨论。结果该病无特异临床表现,术前难以确诊,对该例患者行食管癌根治手术,其组织病理学分析显示未分化癌伴淋巴基质。结论该病组织病理学特点显示为伴有淋巴基质的低分化或未分化癌,治疗以根治性手术为主。其具独特的组织病理学特征,但仍有必要通过一定的标准与其它恶性肿瘤相区别。尽管病理学上表现为高度恶性,但相比普通类型的食管癌患者,食管淋巴上皮瘤样癌预后较好。
The purpose of primary esophageal lymphoepithelioma-like carcinoma is rare, the purpose of this paper is to explore the histopathological features of the disease, and its relationship with Epstein-Barr virus in order to enhance the understanding of the disease. Methods Retrospective analysis of 1 case of primary esophageal lymphoepithelioma carcinoma clinical data, and review the relevant literature for discussion. Results The disease had no specific clinical manifestations and was difficult to diagnose before operation. Radical esophagectomy was performed on this patient. Histopathological analysis showed that undifferentiated carcinoma with lymphatic matrix. Conclusion The histopathological features of the disease showed poorly differentiated or undifferentiated carcinoma with lymphatic matrix. The treatment was mainly radical surgery. Its unique histopathological features, but there is still a need to pass certain criteria and other malignant tumors are different. Despite the high degree of pathological malignancy, esophageal lymphoepithelioma has a better prognosis than ordinary patients with esophageal cancer.