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目的:观察子宫动脉栓塞化疗对中晚期宫颈癌巨块型的治疗效果。方法:对220例治疗前中晚期宫颈癌巨块型患者随机分成两组,对照组110例,行静脉法全身化疗;实验组110例,行双侧子宫动脉超选择栓塞化疗。全部病例完成3疗程(每个疗程间隔28～30天)。在第一疗程化疗后3～4天开始行常规放疗。观察两组病例近期疗效。结果:子宫动脉化疗栓塞与静脉法全身化疗临床有效率分别为(4周)73．6％,8．2％,两组比较有显著性差异( P<0．05)。结论:子宫动脉栓塞化疗能使中晚期宫颈癌巨块型癌灶缩小,减少副反应,减低分期,控制远处转移,有利于放疗的顺利进行。
Objective: To observe the therapeutic effect of uterine artery embolization chemotherapy on the massive type of cervical cancer. Methods: 220 cases of pre-treatment cervical cancer patients with massive block were randomly divided into two groups, control group of 110 cases, intravenous systemic chemotherapy; 110 cases of experimental group, bilateral uterine artery superselective embolization chemotherapy. All cases completed 3 courses (each treatment interval of 28 to 30 days). In the first course of chemotherapy 3 to 4 days after the start of conventional radiotherapy. Observation of two groups of patients with short-term efficacy. Results: The clinical effective rate of uterine arterial chemoembolization and intravenous systemic chemotherapy were 73.6% and 8.2% respectively (4 weeks). There was significant difference between the two groups (P <0.05). Conclusion: Uterine artery embolization chemotherapy can make the large cancerous lesions of cervical cancer shrink in the middle and late stages, reduce the side effects, reduce the staging, and control the distant metastasis, which is favorable for the smooth progress of radiotherapy.