论文部分内容阅读
目的:光学相干断层成像术(optical coherence tomograpy,OCT)测定国人视网膜神经纤维层(reti-nal nerve fiber layer,RNFL)厚度的正常值,为在青光眼早期诊断中的应用奠定基础。方法:使用OCT对77例111只正常眼进行环绕视乳头的RNFL扫描(3.46mm直径),分析不同年龄、性别、眼别RNFL厚度的差异。结果:不同性别、眼别间RNFL的相应厚度无显著差异(P>0.05);各年龄组RNFL厚度平均值(x±s,μm):上象限为128.00±10.31～149.00±13.17、下象限132.95±9.54～142.33±10.60、全周平均RNFL109.00±4.72～114.28±7.98;RNFL随年龄增长有变薄的趋势,以上象限为明显(P<0.05)。结论:OCT检测所得RNFL厚度的均值与性别及眼别无关;应以年龄分组,在本研究的基础上扩大检验的样本数,建立RNFL正常值。眼科学报1998;14:207～209。
OBJECTIVE: To determine the normal thickness of RNFL by optical coherence tomography (OCT) in Chinese people, and to lay the foundation for the early diagnosis of glaucoma. Methods: RNFL scanning (3.46mm in diameter) around the optic nerve of 77 eyes of 111 normal eyes was performed with OCT. The differences in RNFL thickness were analyzed with different age, sex and eyes. Results: There was no significant difference in RNFL thickness between different sexes (P> 0.05). The mean RNFL thickness in each age group (x ± s, μm): the upper quadrant was 128.00 ± 10.31 ~ 149.00 ± 13.17, the lower quadrant was 132.95 ± 9.54 ~ 142.33 ± 10.60, mean global RNFL109.00 ± 4.72 ~ 114.28 ± 7.98; RNFL tended to be thinner with age, and the above quadrant was significantly (P <0.05). CONCLUSION: The mean of RNFL thickness obtained by OCT test has nothing to do with the gender and eyes. The test samples should be expanded by age group to establish the normal value of RNFL. Journal of Ophthalmology 1998; 14: 207 ~ 209.