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Traditional Chinese medicine (TCM) has a glorious history of over 3000 years. The daily increasing demand of Chinese herbal medicine in the world has urged the intational society to pay more attention to TCM, which also means a new opportunity for and challenge to the study and development of TCM. Clinical therapeutic effect is the lifeline of TCM, but the present measurement for clinical effect evaluation fails to reflect the essential effect of TCM. Therefore, how to measure and evaluate objectively the clinical effect of TCM becomes a problem we have to study studiously. World Health Organization (WHO)is very much conced about the clinical effect evaluation of traditional medicines, and has formulated the Guidance of Researches on Safety and Validity Evaluation of Phyto-Drugs(1). In this paper,the authors would mainly discuss the ideas and methods in studying measurement and evaluation of clinical effect of TCM (MECE-TCM) in treating malignant tumor. rn