Abdominal computed tomography in refractory coeliac disease and enteropathy associated T-cell lympho

来源 :World Journal of Gastroenterology | 被引量 : 0次 | 上传用户:caobing1983
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AIM: To evaluate computed tomography (CT) findings, useful to suggest the presence of refractory celiac disease (RCD) and enteropathy associated T cell lymphoma (EATL). METHODS: Coeliac disease (CD) patients were divided into two groups. GroupⅠ: uncomplicated CD (n = 14) and RCD typeⅠ(n = 10). Group Ⅱ: RCD type Ⅱ (n = 15) and EATL (n = 7). RESULTS: Both groups showed classic signs of CD on CT. Intussusception was seen in 1 patient in groupⅠvs 5 in group Ⅱ (P = 0.06). Lymphadenopathy was seen in 5 patients in group Ⅱ vs no patients in groupⅠ(P = 0.01). Increased number of small mesenteric vessels was noted in 20 patients in groupⅠvs 11 in group Ⅱ (P = 0.02). Eleven patients (50%) in group Ⅱ had a splenic volume < 122 cm3 vs 4 in groupⅠ(14%), 10 patients in groupⅠ had a splenic volume > 196 cm3 (66.7%) vs 5 in group Ⅱ (33.3%) P = 0.028. CONCLUSION: CT scan is a useful tool in discriminating between CD and (Pre) EATL. RCD Ⅱ and EATL showed more bowel wall thickening, lymphadenopathy and intussusception, less increase in number of small mesenteric vessels and a smaller splenic volume compared with CD and RCDⅠ. AIM: To computed computed tomography (CT) findings, useful to suggest the presence of refractory celiac disease (RCD) and enteropathy associated T cell lymphoma (EATL). METHODS: Coeliac disease (CD) patients were divided into two groups. Group I: uncomplicated Group Ⅱ: RCD type Ⅱ (n = 15) and EATL (n = 7). RESULTS: Both groups showed classic signs of CD on CT. Intussusception was seen in 1 patient in group I vs 5 in group II (P = 0.06). Lymphadenopathy was seen in 5 patients in group II vs no patients in group I (P = 0.01). Increased number of small mesenteric vessels was noted in 20 patients in group Ivs 11 in group Eleven patients (50%) in group II had a splenic volume <122 cm3 vs 4 in group I (14%), 10 patients in group I had a splenic volume> 196 cm3 (66.7%) vs 5 in Group Ⅱ (33.3%) P = 0.028. CONCLUSION: CT scan is a useful tool in discriminating between CD and (Pre) EATL. RCD Ⅱ and EATL showed more bowel wall thi ckening, lymphadenopathy and intussusception, less increase in number of small mesenteric vessels and a smaller splenic volume compared with CD and RCDI.
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